Pituitary and adrenal hormone responses to pharmacological, physical, and psychological stimulation in habitual smokers and nonsmokers.
Identifieur interne : 000965 ( PubMed/Checkpoint ); précédent : 000964; suivant : 000966Pituitary and adrenal hormone responses to pharmacological, physical, and psychological stimulation in habitual smokers and nonsmokers.
Auteurs : C. Kirschbaum [Allemagne] ; G. Scherer ; C J StrasburgerSource :
- The Clinical investigator [ 0941-0198 ] ; 1994.
English descriptors
- KwdEn :
- Adrenocorticotropic Hormone (secretion), Adult, Circadian Rhythm, Corticotropin-Releasing Hormone, Cotinine (blood), Exercise Test, Growth Hormone (secretion), Humans, Hydrocortisone (analysis), Hydrocortisone (secretion), Male, Nicotine (blood), Pituitary-Adrenal System (drug effects), Pituitary-Adrenal System (secretion), Prolactin (secretion), Saliva (chemistry), Smoking (physiopathology), Stress, Psychological (physiopathology).
- MESH :
- chemical , analysis : Hydrocortisone.
- chemical , blood : Cotinine, Nicotine.
- chemical , secretion : Adrenocorticotropic Hormone, Growth Hormone, Hydrocortisone, Prolactin.
- chemistry : Saliva.
- drug effects : Pituitary-Adrenal System.
- physiopathology : Smoking, Stress, Psychological.
- secretion : Pituitary-Adrenal System.
- Adult, Circadian Rhythm, Corticotropin-Releasing Hormone, Exercise Test, Humans, Male.
Abstract
Hormone responses to injection of corticotropin-releasing hormone following bicycle ergometry and psychological stress were studied in ten habitual smokers and ten nonsmokers. Compared to injection of saline, significant increases were found in adrenocorticotropin, prolactin, growth hormone, total serum cortisol, and salivary cortisol under all three stimulations except for salivary cortisol under ergometry. Furthermore, the smokers showed significant elevations of all five hormones investigated following the smoking of two cigarettes of the subject's preferred brand. Comparisons of hormone responses between smokers and nonsmokers revealed a general trend towards stronger responses in nonsmokers. However, due to the small number of subjects investigated and considerable variation in the individual hormone responses these differences reached statistical significance only for growth hormone responses following ergometry and salivary cortisol responses after psychological stress. In addition, the circadian rhythm of salivary cortisol was measured on two occasions between 9 a.m. and 9 p.m. in the subject's natural environment. The typical circadian pattern of decreasing cortisol levels was observed, with no significant differences between smokers and nonsmokers. We conclude that chronic nicotine consumption may lead to lower responses of multiple hormones not only to nicotine but to a variety of stimuli, and that these alterations do not necessarily affect unstimulated circadian profiles of free cortisol.
PubMed: 7865987
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:7865987Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Pituitary and adrenal hormone responses to pharmacological, physical, and psychological stimulation in habitual smokers and nonsmokers.</title><author><name sortKey="Kirschbaum, C" sort="Kirschbaum, C" uniqKey="Kirschbaum C" first="C" last="Kirschbaum">C. Kirschbaum</name><affiliation wicri:level="1"><nlm:affiliation>Forschungszentrum für Psychobiologie und Psychosomatik, Universität Trier, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Forschungszentrum für Psychobiologie und Psychosomatik, Universität Trier</wicri:regionArea><wicri:noRegion>Universität Trier</wicri:noRegion><wicri:noRegion>Universität Trier</wicri:noRegion><wicri:noRegion>Universität Trier</wicri:noRegion></affiliation></author><author><name sortKey="Scherer, G" sort="Scherer, G" uniqKey="Scherer G" first="G" last="Scherer">G. Scherer</name></author><author><name sortKey="Strasburger, C J" sort="Strasburger, C J" uniqKey="Strasburger C" first="C J" last="Strasburger">C J Strasburger</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1994">1994</date><idno type="RBID">pubmed:7865987</idno><idno type="pmid">7865987</idno><idno type="wicri:Area/PubMed/Corpus">000A00</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000A00</idno><idno type="wicri:Area/PubMed/Curation">000A00</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000A00</idno><idno type="wicri:Area/PubMed/Checkpoint">000A00</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000A00</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Pituitary and adrenal hormone responses to pharmacological, physical, and psychological stimulation in habitual smokers and nonsmokers.</title><author><name sortKey="Kirschbaum, C" sort="Kirschbaum, C" uniqKey="Kirschbaum C" first="C" last="Kirschbaum">C. Kirschbaum</name><affiliation wicri:level="1"><nlm:affiliation>Forschungszentrum für Psychobiologie und Psychosomatik, Universität Trier, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Forschungszentrum für Psychobiologie und Psychosomatik, Universität Trier</wicri:regionArea><wicri:noRegion>Universität Trier</wicri:noRegion><wicri:noRegion>Universität Trier</wicri:noRegion><wicri:noRegion>Universität Trier</wicri:noRegion></affiliation></author><author><name sortKey="Scherer, G" sort="Scherer, G" uniqKey="Scherer G" first="G" last="Scherer">G. Scherer</name></author><author><name sortKey="Strasburger, C J" sort="Strasburger, C J" uniqKey="Strasburger C" first="C J" last="Strasburger">C J Strasburger</name></author></analytic><series><title level="j">The Clinical investigator</title><idno type="ISSN">0941-0198</idno><imprint><date when="1994" type="published">1994</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adrenocorticotropic Hormone (secretion)</term><term>Adult</term><term>Circadian Rhythm</term><term>Corticotropin-Releasing Hormone</term><term>Cotinine (blood)</term><term>Exercise Test</term><term>Growth Hormone (secretion)</term><term>Humans</term><term>Hydrocortisone (analysis)</term><term>Hydrocortisone (secretion)</term><term>Male</term><term>Nicotine (blood)</term><term>Pituitary-Adrenal System (drug effects)</term><term>Pituitary-Adrenal System (secretion)</term><term>Prolactin (secretion)</term><term>Saliva (chemistry)</term><term>Smoking (physiopathology)</term><term>Stress, Psychological (physiopathology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Hydrocortisone</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Cotinine</term><term>Nicotine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="secretion" xml:lang="en"><term>Adrenocorticotropic Hormone</term><term>Growth Hormone</term><term>Hydrocortisone</term><term>Prolactin</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Saliva</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Pituitary-Adrenal System</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Smoking</term><term>Stress, Psychological</term></keywords><keywords scheme="MESH" qualifier="secretion" xml:lang="en"><term>Pituitary-Adrenal System</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Circadian Rhythm</term><term>Corticotropin-Releasing Hormone</term><term>Exercise Test</term><term>Humans</term><term>Male</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Hormone responses to injection of corticotropin-releasing hormone following bicycle ergometry and psychological stress were studied in ten habitual smokers and ten nonsmokers. Compared to injection of saline, significant increases were found in adrenocorticotropin, prolactin, growth hormone, total serum cortisol, and salivary cortisol under all three stimulations except for salivary cortisol under ergometry. Furthermore, the smokers showed significant elevations of all five hormones investigated following the smoking of two cigarettes of the subject's preferred brand. Comparisons of hormone responses between smokers and nonsmokers revealed a general trend towards stronger responses in nonsmokers. However, due to the small number of subjects investigated and considerable variation in the individual hormone responses these differences reached statistical significance only for growth hormone responses following ergometry and salivary cortisol responses after psychological stress. In addition, the circadian rhythm of salivary cortisol was measured on two occasions between 9 a.m. and 9 p.m. in the subject's natural environment. The typical circadian pattern of decreasing cortisol levels was observed, with no significant differences between smokers and nonsmokers. We conclude that chronic nicotine consumption may lead to lower responses of multiple hormones not only to nicotine but to a variety of stimuli, and that these alterations do not necessarily affect unstimulated circadian profiles of free cortisol.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">7865987</PMID><DateCreated><Year>1995</Year><Month>03</Month><Day>28</Day></DateCreated><DateCompleted><Year>1995</Year><Month>03</Month><Day>28</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0941-0198</ISSN><JournalIssue CitedMedium="Print"><Volume>72</Volume><Issue>10</Issue><PubDate><Year>1994</Year><Month>Oct</Month></PubDate></JournalIssue><Title>The Clinical investigator</Title><ISOAbbreviation>Clin Investig</ISOAbbreviation></Journal><ArticleTitle>Pituitary and adrenal hormone responses to pharmacological, physical, and psychological stimulation in habitual smokers and nonsmokers.</ArticleTitle><Pagination><MedlinePgn>804-10</MedlinePgn></Pagination><Abstract><AbstractText>Hormone responses to injection of corticotropin-releasing hormone following bicycle ergometry and psychological stress were studied in ten habitual smokers and ten nonsmokers. Compared to injection of saline, significant increases were found in adrenocorticotropin, prolactin, growth hormone, total serum cortisol, and salivary cortisol under all three stimulations except for salivary cortisol under ergometry. Furthermore, the smokers showed significant elevations of all five hormones investigated following the smoking of two cigarettes of the subject's preferred brand. Comparisons of hormone responses between smokers and nonsmokers revealed a general trend towards stronger responses in nonsmokers. However, due to the small number of subjects investigated and considerable variation in the individual hormone responses these differences reached statistical significance only for growth hormone responses following ergometry and salivary cortisol responses after psychological stress. In addition, the circadian rhythm of salivary cortisol was measured on two occasions between 9 a.m. and 9 p.m. in the subject's natural environment. The typical circadian pattern of decreasing cortisol levels was observed, with no significant differences between smokers and nonsmokers. We conclude that chronic nicotine consumption may lead to lower responses of multiple hormones not only to nicotine but to a variety of stimuli, and that these alterations do not necessarily affect unstimulated circadian profiles of free cortisol.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kirschbaum</LastName><ForeName>C</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Forschungszentrum für Psychobiologie und Psychosomatik, Universität Trier, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scherer</LastName><ForeName>G</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Strasburger</LastName><ForeName>C J</ForeName><Initials>CJ</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016430">Clinical Trial</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016449">Randomized Controlled Trial</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Clin Investig</MedlineTA><NlmUniqueID>9207154</NlmUniqueID><ISSNLinking>0941-0198</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>6M3C89ZY6R</RegistryNumber><NameOfSubstance UI="D009538">Nicotine</NameOfSubstance></Chemical><Chemical><RegistryNumber>9002-60-2</RegistryNumber><NameOfSubstance UI="D000324">Adrenocorticotropic Hormone</NameOfSubstance></Chemical><Chemical><RegistryNumber>9002-62-4</RegistryNumber><NameOfSubstance UI="D011388">Prolactin</NameOfSubstance></Chemical><Chemical><RegistryNumber>9002-72-6</RegistryNumber><NameOfSubstance UI="D013006">Growth Hormone</NameOfSubstance></Chemical><Chemical><RegistryNumber>9015-71-8</RegistryNumber><NameOfSubstance UI="D003346">Corticotropin-Releasing Hormone</NameOfSubstance></Chemical><Chemical><RegistryNumber>K5161X06LL</RegistryNumber><NameOfSubstance UI="D003367">Cotinine</NameOfSubstance></Chemical><Chemical><RegistryNumber>WI4X0X7BPJ</RegistryNumber><NameOfSubstance UI="D006854">Hydrocortisone</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000324" MajorTopicYN="N">Adrenocorticotropic Hormone</DescriptorName><QualifierName UI="Q000557" MajorTopicYN="N">secretion</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002940" MajorTopicYN="N">Circadian Rhythm</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003346" MajorTopicYN="Y">Corticotropin-Releasing Hormone</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003367" MajorTopicYN="N">Cotinine</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005080" MajorTopicYN="N">Exercise Test</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013006" MajorTopicYN="N">Growth Hormone</DescriptorName><QualifierName UI="Q000557" MajorTopicYN="N">secretion</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006854" MajorTopicYN="N">Hydrocortisone</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName><QualifierName UI="Q000557" MajorTopicYN="N">secretion</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009538" MajorTopicYN="N">Nicotine</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010913" MajorTopicYN="N">Pituitary-Adrenal System</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName><QualifierName UI="Q000557" MajorTopicYN="Y">secretion</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011388" MajorTopicYN="N">Prolactin</DescriptorName><QualifierName UI="Q000557" MajorTopicYN="N">secretion</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012463" MajorTopicYN="N">Saliva</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012907" MajorTopicYN="N">Smoking</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013315" MajorTopicYN="N">Stress, Psychological</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1994</Year><Month>10</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1994</Year><Month>10</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1994</Year><Month>10</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">7865987</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li></country></list><tree><noCountry><name sortKey="Scherer, G" sort="Scherer, G" uniqKey="Scherer G" first="G" last="Scherer">G. Scherer</name><name sortKey="Strasburger, C J" sort="Strasburger, C J" uniqKey="Strasburger C" first="C J" last="Strasburger">C J Strasburger</name></noCountry><country name="Allemagne"><noRegion><name sortKey="Kirschbaum, C" sort="Kirschbaum, C" uniqKey="Kirschbaum C" first="C" last="Kirschbaum">C. Kirschbaum</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Rhénanie/explor/UnivTrevesV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000965 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 000965 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Rhénanie
|area= UnivTrevesV1
|flux= PubMed
|étape= Checkpoint
|type= RBID
|clé= pubmed:7865987
|texte= Pituitary and adrenal hormone responses to pharmacological, physical, and psychological stimulation in habitual smokers and nonsmokers.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:7865987" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a UnivTrevesV1
| This area was generated with Dilib version V0.6.31. |  |